CNTs are now subject to significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA). The SNURs require persons who intend to manufacture (defined by statute to include import) or process any of these chemical substances for an activity that is proposed as a significant new use by this rule to notify EPA at least 90 days before commencing that activity Pre-manufacture Notice (PMN)

Results of chronic aquatic toxicity testing, with natural organic matter (NOM) as the dispersant, may be potentially useful to characterize the environmental effects of the PMN substance.

TSCA requires:

•Use of personal protective equipment where there is a potential for dermal exposure;
•Use of a National Institute for Occupational Safety and Health (NIOSH)-certified respirator with an Assigned Protection Factor (APF) of at least 50 where there is a potential for inhalation exposure;
•Use of the PMN substance other than as allowed in the TSCA Order;
•Waste streams from manufacture, processing, and use must be disposed of only by incineration or landfill;
•No predictable or purposeful release of a manufacturing, processing, or use stream associated with any use of the PMN substance into the waters of the United States.
Full details HERE.