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US NTP Centre determining Technical Needs for non-Animal System that can assess potential Toxicity of Nano

The US National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) recently requested ‘data and information on devices and/or technologies currently used for identifying potential inhalation hazards’. The agency received a number of responses, and this data is set to be used ‘to assess the state of the science and determine the technical needs for a dynamic non-animal system to assess the potential toxicity of inhaled chemicals or nanomaterials’.

Information sent to the Centre ‘could describe activities relevant to the development or validation of alternatives to in vivo inhalation toxicity tests currently required by regulatory agencies, or submission of data from non-animal tests for identifying acute inhalation hazard potential’. Responses were due by mid-July 2014.

NICEATM, funded by the US Department of Health and Human Services, ‘fosters the evaluation and promotion of alternative test methods for regulatory use in acute toxicity assessment’. To date, the Centre has ‘focused primarily on toxicity testing for assessing potential hazards via the oral and dermal routes with limited efforts directed to identifying alternatives for assessing inhalation toxicity’.


Follow this link to read the request, this to view all the responses, and this to learn more about NICEATM.

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