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How to test manufactured Nanomaterials: OECD Published Updates and Test Protocols
Published: Tuesday 15 June 2010
The OECD Working Party of Manufacture Nanomaterials (WPMN) has added two documents to its OECD Publication Series on the Safety of Manufactured Nanomaterials:
1. OECD WPMN Publication Number 24: ‘Preliminary Guidance Notes on Sample Preparation and Dosimetry for the Safety Testing of Manufactured Nanomaterials’.
Text excerpts:
‘The WPMN recognised that it was essential to develop a guidance document on sample preparation and dosimetry, based on the discussion held in preparing the ‘Preliminary Review of OECD Test Guidelines for their Applicability to Manufactured Nanomaterials.’ It called special attention to this guidance as crucial in using test guidelines when considering the unique chemical and physical characteristics of nanomaterials.
It is important to note that this document [...] is a “living document” and as such, it will be updated and amended based upon knowledge accumulation and evolving communication and as experience is gained with nanomaterial testing.’
Additional, specific guidance and protocols on sample preparation, dosimetry and characterisation of nanomaterials has been developed by PROSPEcT - Ecotoxicology Test Protocols for Representative Nanomaterials in Support of the OECD Sponsorship Programme; follow these links to download a Protocol for Nanoparticle Dispersion, Guidelines and Protocol for Sampling, or to watch a Dispersion Protocol Video.
2. An updated version of the OECD WPMN Publication Number 14 ‘Guidance Manual for the Testing of Manufactured Nanomaterials: OECD's Sponsorship Programme’; according to the Executive Summary, the OECD WPMN Publication Number 25: ‘Guidance Manual for the Testing of Manufactured Nanomaterials: OECD Sponsorship Programme: First Revision’ , the revised version contains 'a Data Sharing Template Format , [which] was finalised at the 6th meeting in October 2009 and it was agreed to its inclusion to this documentas an annex (Annex III).'
The following additions were made during the 1st revision:
- ANNEX III: Data Sharing Template Format
- PART I: Essential Elements for the Dossier and Template
- PART II: Examples
- Example: Acute toxicity to fish
- Example: Mammalian Toxicity: Repeated Dose Toxicity
- PART III: Draft Proposal for Data Sharing Format for non-standardised Test Methods
- ANNEX IV: Alternative Test Methods in the Sponsorship Programme
Follow these links to access all OECD WPMN Publications, or to find out more about the OECD Publication Series on the Safety of Manufactured Nanomaterials.
Tags: OECD Working Party on Manufactured Nanomaterials, OECD WPMN, OECD WPMN Sponsorship Programme