The RefNanoCLAYM Project is a NIA-initiated and -led public-private-partnership aiming to assess a naturally occurring clay (i.e. a bentonite) with regard to the endpoints agreed under the OECD WPMN Sponsorship Programme. The PPP's partners are renoun national measurement and testing laboratories, which characterise the physico-chemical properties of this commercially utilised bentonite, as well as those in commercially relevant media.
Environmental fate and ecotoxicological behaviour are investigates in a step-wise approach: In the first step, standard toxicity tests according to OECD test guidelines are proposed, while in the second step, adaptations of test protocols according to procedures elaborated for other Representative Manufacture Nanomaterials (RMNs) under the OECD WPMN Sponsorship Programme, will be considered.
A variety of terrestrial and aquatic test organisms will be selected to get information concerning potential ecotoxicological effects. Besides short-term tests according to the basic procedure used for chemicals testing, aquatic and terrestrial long-term tests are proposed.
NIA holds the Lead-Sponsorship of the nano-Clay Consortium at the OECD WPMN Sponsorship Programme.
The nanomaterial used in the RefNanoCLAYM Project has been endorsed as a Principal Material under the OECD WPMN Sponsorship Programme; as NM-600 Bentonite, it is sub-sampled by and held at the European Repository of NM-Series of Representative Manufactured Nanomaterials.